Cranial and Spinal Meningiomas: A 21-Year Single-Center Analysis of 108 Consecutive Patients in Tu¨ rkiye
Hasan Ali Aydin, Emrah Keskin, Murat Kalayci
article (Uluslararası, Hakemli) | Yazar(lar): Hasan Ali Aydin, Emrah Keskin, Murat Kalayci | Yıl: 2026 | Dergi/Kurum: WORLD NEUROSURGERY | İndeks: WOS.SCI | DOI: 10.1016/j.wneu.2026.125265 | Anahtar Kelimeler: Meningioma, Recurrence, Retrospective cohort, Simpson grade, Surgical outcome, T & uuml;rkiye, WHO classificat
square BACKGROUND: Single-center series remain useful for benchmarking local practice against the published literature. We report a 21-year experience with cranial and spinal meningiomas at one tertiary center in T & uuml;rkiye. square METHODS: We retrospectively reviewed 108 consecutive patients operated for histopathologically confirmed cranial or spinal meningioma at Zonguldak B & uuml;lent Ecevit University, T & uuml;rkiye, from January 2002 to December 2023. Clinical, histopathological (2021 World Health Organization classification), and surgical (Simpson grade) data were summarized descriptively; recurrence was explored by location and extent of resection using Fisher's exact test. square RESULTS: The cohort comprised 76 women and 32 men (mean age 59 years); 86 tumors (80%) were World Health Organization grade 1. Simpson grade I resection was achieved in 68 patients (63%) overall, but in only 4 of 32 skull-base tumors (13%) versus 60 of 72 nonskull-base tumors (83%). The postoperative course was favorable in 86 patients (80%); complications occurred in 14 (13%); inhospital and 30-day mortality were 2.8% (3/108) and 0.9% (1/108), respectively. Over a median follow-up of 83 months in 75 patients, recurrence was documented in 9 (8.3%), more often in skull-base tumors (19% vs. 4.2%; odds ratio, 5.3; 95% confidence interval, 1.2-22.8; P = 0.023), but not by the extent of resection (odds ratio, 2.9; 95% confidence interval, 0.5-15.9; P = 0.23). square CONCLUSIONS: In our hands, complete resection was achieved in most nonskull-base tumors but rarely at the skull base, and mortality was confined to patients presenting with a marked neurological deficit. The clustering of recurrence in skull-base tumors rests on 9 events and incomplete follow-up and describes our experience rather than a generalizable finding.