Effect of Channel Noise and Dynamic Synapse Structure on Latency Dynamics in Neural System
Ali Calim, Muhammet Uzuntarla, M Özer, None None
proceeding (Uluslararası, Hakemli) | Yazar(lar): Ali Calim, Muhammet Uzuntarla, M Özer, None None | Yıl: 2018 | Dergi/Kurum: 2018 26TH SIGNAL PROCESSING AND COMMUNICATIONS APPLICATIONS CONFERENCE (SIU) | İndeks: WOS.ISTP | Anahtar Kelimeler: first spike, dynamic synapse, channel noise — Özet: Experimental and theoretic
Experimental and theoretical studies in recent years suggest that the first spike latency is an effective information carrier and contains more neural information than other spikes. Noise Delayed Decay (NDD) phenomenon emerges when the first spike latency of the neuron exposed to the periodic driving is maximum at a certain noise intensity interval. In this study, the latency dynamics of a single Hodgkin-Huxley neuron is investigated under periodic driving, background activity through dynamic synapses, and channel noise. The system response with first spike latency is investigated as a function of the presynaptic firing rate, the parameter with an appropriate biophysical reality to control the level of activity in the nervous system. First, NDD behavior is investigated under suprathreshold stimulation in the presence of synapses at different levels of depression and channel noise. It is then desired to observe the NDD phenomenon under subthreshold stimulation with the same strategy. Our results have shown that the background activity occurring in the presence of dynamic synapses and the channel noise are significant system dynamics in observing the NDD behavior.