The relationship of Charlson comorbidity index with stent restenosis and extent of coronary artery disease
Turgut Karabag, Belma Kalayci, Bahar Sahin, Mustafa Umut Somuncu, Mustafa Ozan Cakir, Emine Altuntas
article (Uluslararası, Hakemli) | Yazar(lar): Turgut Karabag, Belma Kalayci, Bahar Sahin, Mustafa Umut Somuncu, Mustafa Ozan Cakir, Emine Altuntas | Yıl: 2018 | Dergi/Kurum: INTERVENTIONAL MEDICINE AND APPLIED SCIENCE | İndeks: WOS.ESCI | DOI: 10.1556/1646.10.2018.20 | Anahtar Kelimeler: coronary artery disease, Charls
Objectives: The objective of this study is to investigate the effect of comorbid conditions [Charlson comorbidity index (CCI)] on stent restenosis who underwent coronary angioplasty earlier. Methods: Patients were divided into two groups; patients with critical restenosis [recurrent diameter stenosis >50% at the stent segment or its edges (5-mm segments adjacent to the stent) (Group 1; n = 53, mean age: 63.8 +/- 9.9 years)] and patients with no critical restenosis [< 50% obstruction (Group 2; n = 94, mean age: 62.1 +/- 9.1 years)]. The CCI and modified CCI were used for the presence of comorbid conditions. The Gensini scoring system was used to assess the extent of coronary artery disease (CAD). Results: Group 1 had a significantly greater CCI and modified CCI score compared to Group 2 (7.1 +/- 3.7 vs. 5.6 +/- 1.6, p = 0.006; 6.9 +/- 3.6 vs. 4.5 +/- 1.5, p = 0.008, respectively). There was a weak correlation, albeit significant, between the modified CCI score and restenosis percentage (r = 0.29, p < 0.001; r = 0.25, p = 0.003, respectively). Conclusions: In conclusion, the CCI score is greater among patients with stent restenosis than those without. CCI score is higher among patients with a more diffuse CAD than with a milder disease extent.