Different IgE reactivity profiles in the patients who sensitized to Betula pendula Roth (syn = B. verrucosa) pollen
Senol Alan, Ozlem Yildirim, NM Pinar, Derya Secil, Zeynep Misirligil, Tamer Keceli, Talip Ceter
article (Uluslararası, Hakemli) | Yazar(lar): Senol Alan, Ozlem Yildirim, NM Pinar, Derya Secil, Zeynep Misirligil, Tamer Keceli, Talip Ceter | Yıl: 2009 | Dergi/Kurum: ASTIM ALLERJI IMMUNOLOJI | İndeks: WOS.ESCI | Anahtar Kelimeler: Betula pendula, pollen, immunoglobulin E, Bet v 1 allergen, Bet v 2 allergen — Özet: O
Objective: IgE reactivity has been investigated in the patients who sensitized to Betula pendula Roth (syn= B. verrucosa) pollen that distributed widely in nature habitat and also in park and gardens in Turkey. Materials and
Methods: Protein profile of pollen was studied by SDS-PAGE and transferred to polyvinylidenfluorid (PVDF) membrane. IgE reactivity profiles have been assessed via 10 patients who sensitized to pollen.
Results: It has been found that 86% (n= 6) show a positive reaction to 17 kDa (Bet v 1), 29% (n= 2) of sensitized seven patients has show a positive reaction to 15 kDa (Bet v 2). Only one patient show a reaction to protein which has 14.5 kDa molecular weight.
Conclusion: Our preliminary results have shown that the most common IgE reactivitiy was against sinde en sik IgE reaktivitesinin Bet v 1'e karsi oldugunu gustermistir.