Effects of Autaptic Coupling Stregth and Ion Channel Blockage on Firing Regularity in a Hodgkin-Huxley Neuron
Rukiye Uzun, M Özer, None None
proceeding (Uluslararası, Hakemli) | Yazar(lar): Rukiye Uzun, M Özer, None None | Yıl: 2017 | Dergi/Kurum: 2017 25TH SIGNAL PROCESSING AND COMMUNICATIONS APPLICATIONS CONFERENCE (SIU) | İndeks: WOS.ISTP | Anahtar Kelimeler: Autapse, channel blockage, Hodgkin-Huxley neuron model — Özet: We investigate how firing dynamic
We investigate how firing dynamics of neuron changes with the autpse's coupling strength for different ratio of the blockage of potassium and sodium ion channels embedded in membranes affects, with using a biophysically more realistic Hodgkin-Huxley neuron model. In the study, we assume that neuron has an excitatory chemical autapse. It is found that the neuron dynamics does not change for too small coupling strength whether it increases after a certain coupling strength' value in case of different ion channel blockage case. Besides, it is determined that potassium ion channel blockage has a healing effect whereas sodium ion channel blockage has a destructive effect on the neuron dynamics increasing with the autaptic coupling strength.