Acute Kidney Injury Related to Intravenous Immunoglobulin Therapy: A Case Report
Fatih Yilmaz, Muammer Bilici, Sebnem Karacay Ozkalayci, Oguz Guven
article (Uluslararası, Hakemli) | Yazar(lar): Fatih Yilmaz, Muammer Bilici, Sebnem Karacay Ozkalayci, Oguz Guven | Yıl: 2017 | Dergi/Kurum: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL | İndeks: WOS.ESCI | DOI: 10.5262/tndt.2017.1002.18 | Anahtar Kelimeler: Acute kidney injury, Guillain-Barre syndrome, Intra
Intravenous immunoglobulin (IVIG) has been developed for the treatment of hypogammaglobulinemia and is also used for many systemic inflammatory and autoimmune disorders. Acute kidney injury is a rare complication of the use of IVIG, and is mainly caused by stabilizing agents in the protein formulation. A complete recovery of renal function is seen within days. We present the case of an 81-year old woman, treated for acute inflammatory demyelinating polyneuropathy (Guillain-Barre syndrome) that caused loss of sensation and muscle weakness in the leg. She was treated with IVIG for five days. Renal failure developed during treatment. The patient's acute kidney injury resolved a month later. The patients should be monitored closely after IVIG therapy for renal injury.