A new lateral thoracic artery perforator flap design with multiple vascular territories in rats
Seckin Aydin Savas, Ibrahim Cumhur Bassorgun, Arzu Akcal, Tahsin Gorgulu
article (Uluslararası, Hakemli) | Yazar(lar): Seckin Aydin Savas, Ibrahim Cumhur Bassorgun, Arzu Akcal, Tahsin Gorgulu | Yıl: 2017 | Dergi/Kurum: JOURNAL OF SURGICAL RESEARCH | İndeks: WOS.SCI | DOI: 10.1016/j.jss.2016.08.066 | Anahtar Kelimeler: Lateral thoracic artery, perforator flap rat — Özet: Background: To descr
Background: To describe a new design for an extended lateral thoracic artery (LTA) perforator flap and investigate its anatomical, dynamic, and potential territories.
Materials and methods: To assess vascular territories, rats were randomized according to LTA perforator flap type into the surgical groups A, hemidorsal island flap; B, entire dorsal island flap; and C, reduced-size dorsal island flap.
Results: On postsurgical day 7, the surviving flap areas were 95%, 92%, and 89% in groups A, B, and C, respectively. Necrosis most commonly occurred in the contralateral LTA territories in groups B and C. The immunoreactivities of intercellular adhesion molecule 1 and vascular endothelial growth factor receptor 2 in dynamic territories, as choke vessel markers, were increased.
Conclusions: We clarified the LTA perforator flap nomenclature and defined its pedicle course and anastomosing patterns; furthermore, we demonstrated that the LTA perforator did not anastomose with its counterpart because of its unidirectional, oblique, and craniocaudal course. The LTA perforator flap was found to be a good model comprising multiple vascular territories and exhibiting continuous necrosis. (C) 2016 Elsevier Inc. All rights reserved.