Does adenosine deaminase activity play a role in the early diagnosis of ectopic pregnancy?
G. G. Turkmen, D. Karcaaltincaba, H. Isik, S. Batioglu, V. Fidanci, D. Kaayalp, Hakan Timur
article (Uluslararası, Hakemli) | Yazar(lar): G. G. Turkmen, D. Karcaaltincaba, H. Isik, S. Batioglu, V. Fidanci, D. Kaayalp, Hakan Timur | Yıl: 2016 | Dergi/Kurum: JOURNAL OF OBSTETRICS AND GYNAECOLOGY | İndeks: WOS.SCI | DOI: 10.3109/01443615.2015.1065228 | Anahtar Kelimeler: ectopic pregnancy, pregnancy complication
Early diagnosis of ectopic pregnancy (EP) is important due to life-threatening consequences in the first trimester of pregnancy. In this study we aimed to investigate the role of adenosine deaminase (ADA) activity in the prediction of EP. Forty-one patients with unruptured ectopic pregnancy comprised the case group and forty-two first trimester pregnant women with shown foetal heart beating in ultrasound comprised the control group. The mean ADA level in EP (10.9 +/- 3.0 IU/L) was higher than that in control group (9.2 +/- 3.6 IU/L) (p = 0.018). Receiver operating characteristics or ROC curve identified ADA value of 10.95 IU/L as optimal threshold for the prediction of EP with 56% sensitivity and 67% specificity. High ADA levels are valuable in the early diagnosis of EP. However more comprehensive studies are required.