Sage oil extraction and optimization by response surface methodology
Mehmet Kuddusi Akalin, Kubilay Tekin, Mehmet Akyuz, Selhan Karagoz
article (Uluslararası, Hakemli) | Yazar(lar): Mehmet Kuddusi Akalin, Kubilay Tekin, Mehmet Akyuz, Selhan Karagoz | Yıl: 2015 | Dergi/Kurum: INDUSTRIAL CROPS AND PRODUCTS | İndeks: WOS.SCI | DOI: 10.1016/j.indcrop.2015.08.005 | Anahtar Kelimeler: Supercritical fluid extraction, Sage, Box-Behnken design, Response surface
Sage oil extraction is important as most of the components in sage play an important role in the treatment of various diseases. The aim of the present study was to optimize supercritical extraction parameters for sage (Salvia officinalis L.) oil yield by response surface methodology. A 3-factor Box-Behnken design was used to generate factor combinations. The optimal conditions for the sage oil extraction yield were 2800 degrees C extraction temperature, 110 min extraction time and 11% (wt/v) plant concentration in ethanol. The validation experiment showed that the actual and predicted values were 49.21 and 47.04 wt%, respectively. The composition of sage essential oil consisted mainly of acid esters together with phenols, limonene, indoles, and pyrroles. These compounds can be used in various industrial applications. (C) 2015 Elsevier B.V. All rights reserved.