The Mean Platelet Volume and Atherogenic Index of Plasma in Nondipper Normotensive Individuals Compared to Dippers
G. Yildiz, E. Hur, Adalet Ozcicek, Ferhan Candan, Mansur Kayatas
article (Uluslararası, Hakemli) | Yazar(lar): G. Yildiz, E. Hur, Adalet Ozcicek, Ferhan Candan, Mansur Kayatas — Özet: Mean platelet volume (MPV) is a determinant of platelet activation. Atherogenic index of plasma (AIP), which is defined as the logarithm of the ratio of plasma level of triglycerides to the level of hi
Mean platelet volume (MPV) is a determinant of platelet activation. Atherogenic index of plasma (AIP), which is defined as the logarithm of the ratio of plasma level of triglycerides to the level of high-density lipoprotein (HDL)-cholesterol (log[TG/HDL-C]), has recently been used as a marker of atherogenicity. This study included 104 normotensive individuals. Mean platelet volume and AIP were measured in all patients. Nondipper individuals (8.6 +/- 0.9 fL, 0.3 +/- 0.2) demonstrated higher values of MPV and AIP compared with dippers (7.9 +/- 1.1 fL, 0.1 +/- 0.2) (P<.001 and <.001, respectively). Mean platelet volume and AIP have a positive correlation with insufficient decline in nocturnal blood pressure.