Evaluation of the relationship between heart type fatty acid binding protein levels and the risk of maternal cardiac ischemia in low risk obstetric population during delivery
Suleyman Akarsu, Sevgi Ture, Veciha Ozlem Akcinar, Ahmet Arif Yalcin, Cemil Bilir, Nermin Akdemir, Arif Serhan Cevrioglu, Selcuk Ozden, Murat Yucel, Yusuf Yurumez
article (Uluslararası, Hakemli) | Yazar(lar): Suleyman Akarsu, Sevgi Ture, Veciha Ozlem Akcinar, Ahmet Arif Yalcin, Cemil Bilir, Nermin Akdemir, Arif Serhan Cevrioglu, Selcuk Ozden, Murat Yucel, Yusuf Yurumez | Yıl: 2012 | Dergi/Kurum: MEDICINSKI GLASNIK | İndeks: WOS.SCI | Anahtar Kelimeler: delivery, h-FABP, troponin
Aim To investigate the heart type fatty acid binding protein (hFABP) changes during delivery in low-risk obstetric population.
Methods Pregnant women who are at term and met the inclusion criteria were included the study. Maternal echocardiography, electrocardiography, arterial blood pressure monitoring, CK-MB, serum heart type fatty acid binding protein and troponin 1 levels were evaluated before and after delivery. Of the total of 100 pregnant women, mean age was 26.7 +/- 5, 51 pregnant had vaginal delivery and the remaining 49 had caesarean section.
Results The h-FABP positivity was detected in nine (9%) subjects after the delivery as compared to values before the delivery (p=0.0035). Troponin levels were 0.013 +/- 0.001 before the delivery and 0.025 +/- 0.002 after the delivery (p=0.0001). In the comparison of vaginal and Cesarean deliveries, h-FABP positivity was detected in five of 51 subjects in the vaginal delivery group and four of 49 subjects in the cesarean delivery group (p=0.95). The changes in troponin levels were 0.01 ng/mL (-0.02 to 0.2) in the vaginal delivery group and 0.01ng/mL (-0.07 to 0.06) in the cesarean delivery group (p=0.24).
Conclusion Delivery stress is associated with maternal cardiac damage as evaluated by heart type fatty acid binding protein and troponin. There was no difference between the two delivery routes in the risk of maternal cardiac damage.