Gemcitabine-Cisplatin Induced Acute Pancreatitis: a Case Report
Cemil Bilir, Huseyin Engin, Hasan Ustun, Y Ustundag
article (Uluslararası, Hakemli) | Yazar(lar): Cemil Bilir, Huseyin Engin, Hasan Ustun, Y Ustundag | Yıl: 2012 — Özet: Background: Many drugs can cause acute pancreatitis, also this phenomenon rarely with chemotherapeutic compounds. Several reports of pancreatitis following the use of chemotherapy drugs but pancreatitis
Background: Many drugs can cause acute pancreatitis, also this phenomenon rarely with chemotherapeutic compounds. Several reports of pancreatitis following the use of chemotherapy drugs but pancreatitis has not been reported with gemcitabine and cisplatin
Case: A 68-year-old female diagnosed bone metastatic lung cancer. She was started on chemotherapy with a regimen of gemcitabine and cisplatin (GC). On second day of the 1st dose of GC, patient was admitted to the hospital and subsequent workup revealed acute pancreatitis.
Conclusions: This is the first case report of acute pancreatitis caused by gemcitabine-cisplatin regimen. When a patient experience prolonged nausea and vomiting follwed to the chemothreapy regimen, acute pancreatitis come to mind to prevent fatal complications.