Lower limits of detection in speciation analysis by coupling high-performance liquid chromatography and chemical-vapor generation
Yasin Arslan, Emrah Yildirim, Sezgin Bakirdere, Mehrdad Gholami
article (Uluslararası, Hakemli) | Yazar(lar): Yasin Arslan, Emrah Yildirim, Sezgin Bakirdere, Mehrdad Gholami | Yıl: 2011 | Dergi/Kurum: TRAC-TRENDS IN ANALYTICAL CHEMISTRY | İndeks: WOS.SCI | DOI: 10.1016/j.trac.2010.11.017 | Anahtar Kelimeler: Arsenic, Atomic absorption spectrometry, Atomic fluorescence spectroscopy,
Speciation studies are much more important than total element determination because toxicity of many elements depends on their chemical forms. Nobody can claim that a foodstuff is very dangerous to eat by determining total arsenic due to the possibility that the arsenic could be present in non-toxic forms. Hence, speciation studies are crucial in any matrix relevant to human beings.
Trace-element speciation requires sufficiently sensitive procedures to monitor each species at trace levels. One way to increase the sensitivity for elements forming volatile species is coupling high-performance liquid chromatography (HPLC) with chemical-vapor generation (CVG). This review aims to highlight not only development of HPLC-CVG techniques for ultratrace-elemental speciation in a variety of matrices but also their application. In addition, we discuss the advantages and the disadvantages of these techniques. (C) 2011 Elsevier Ltd. All rights reserved.