Functional association of interleukin-18 gene-607 C/A promoter polymorphisms with endometriosis
Filiz Cayan, Lokman Ayaz, Lulufer Tamer, Nurcan Aras-Ates, Sevim Karakas Celik
editorial (Uluslararası, Hakemli) | Yazar(lar): Filiz Cayan, Lokman Ayaz, Lulufer Tamer, Nurcan Aras-Ates, Sevim Karakas Celik | Yıl: 2011 | Dergi/Kurum: FERTILITY AND STERILITY | İndeks: WOS.SCI | DOI: 10.1016/j.fertnstert.2010.07.1046 | Anahtar Kelimeler: Cytokines, endometriosis, interleukin-18, polymorphism — Özet:
This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607*A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis. (Fertil Steril (R) 2011; 95:298-300. (c) 2011 by American Society for Reproductive Medicine.)