Co-morbidity of panic disorder with or without agoraphobia
Irem Yalug, Umit Tural, Eylem Oezten, Ali Evren Tufan, Tamer Aker, N Atasoy, N Konuk, Ayten ErdoGan
article (Uluslararası, Hakemli) | Yazar(lar): Irem Yalug, Umit Tural, Eylem Oezten, Ali Evren Tufan, Tamer Aker, N Atasoy, N Konuk, Ayten ErdoGan | Yıl: 2007 | Dergi/Kurum: NEUROLOGY PSYCHIATRY AND BRAIN RESEARCH | İndeks: WOS.SCI, WOS.SSCI | Anahtar Kelimeler: agoraphobia, comorbidity, panic disorder, prevalence — Öze
Objective: This study evaluated the clinical and sociodemographic features associated with concurrent Axis I psychiatric disorders among adult psychiatric outpatients with panic disorder (PD) with or without agoraphobia (AG).
Method: This was a retrospective chart review study of 12.980 patients treated for any psychiatric disorders in psychiatric outpatient clinics. Diagnoses of comorbid disorders were determined in a sample of 478 patients with panic disorder as defined in DSM-IV The subjects were divided into two groups: patients panic disorder with AG (n=221) and panic disorder without AG (n=254). Sociodemographic variables, illness characteristics such as symptoms, duration of illnes and family history of psychiatric disorders were evaluated.
Results: Panic disorder was prevalent among 3.7 % of the sample. The most common Axis I psychiatric disorders among groups were major depressive disorder (21.7 %) and generalized anxiety disorder (8.9 %). The prevalence of other psychiatric disorders in present study was as follows: social phobia 7.3 %; obsessive-compulsive disorder 4.6 %; posttraumatic stress disorder 4.6 %; eating disorders 1.46 %; alcohol abuse/dependence 4.6 %; somatoform disorders 0.85 %; bipolar disorder 0.6 %; dysthymic disorder 2.3 % and impulse control disorder 0.4 %. Female subjects have higher comorbid conditions compared to males. Those with more concurrent Axis I conditions had longer histories of PD and younger age of onset.
Conclusion: These data are consistent with previous clinical findings by showing that panic disorder is associated with increased likelihood of a range of affective and anxiety disorders, among psychiatric patients population. These findings have implications for clinical practice in that PD patients with or without AG should be carefully assessed for the comorbidity of psychiatric disorders, because they may all effect the course of illness.