The synthesis of 2-(Chloromethyl)-6-Hydroxy-<i>2H</i>-Pyran-3 (6H)-one via achmatowicz rearrangement
Z Gercek
article (Uluslararası, Hakemli) | Yazar(lar): Z Gercek | Yıl: 2007 | Dergi/Kurum: TURKISH JOURNAL OF CHEMISTRY | İndeks: WOS.SCI | Anahtar Kelimeler: oxidation, furan, 2-chloro-1-(furan-2-yl) ethanol, m-CPBA, rearrangement, pyranones — Özet: Achmatowicz rearrangement was carried out with 2-chloro-1-(furan-2-yl) ethanol
Achmatowicz rearrangement was carried out with 2-chloro-1-(furan-2-yl) ethanol, which was synthesized starting from 1-(furan-2-yl) ethanone. It was shown that the oxidation of 2-chloro-1-(furan-2-yl) ethanol with m-CPBA produced 2-(chloromethyl)-6-hydroxy-2H-pyran-3 (6H)-one in good yield (70%).