Diurnal variation of the P-wave dispersion in chronic ischemic heart diseases
Nesligul Yildirim, Serkan Topaloglu, Seher Bozboga, Arslan Ocal, Ersin Saricam
article (Uluslararası, Hakemli) | Yazar(lar): Nesligul Yildirim, Serkan Topaloglu, Seher Bozboga, Arslan Ocal, Ersin Saricam | Yıl: 2006 | Dergi/Kurum: CORONARY ARTERY DISEASE | İndeks: WOS.SCI | Anahtar Kelimeler: coronary heart disease, P-wave dispersion, P-wave duration — Özet: Objective Electrocardiographic indices
Objective Electrocardiographic indices like maximum P-wave duration (P-max) and P-wave dispersion (PD) can be used to detect patients with atrial conduction disorders, myocardial ischemia and those at risk for atrial fibrillation. Considering the diurnal variation of ischernia in patients with significant coronary lesions, this study was designed to investigate the diurnal variation of eventual atrial conduction abnormalities.
Methods Forty-eight patients (31 male) with typical angina were grouped according to coronary angiography results as group 1 - 70% or more luminal reduction in at least one of the coronary arteries (n=28), and group 2 - normal coronary arteries (n = 20). The difference between the P-max and minimum P-wave durations (P-min) is designated as PD. The diurnal P-max, Pmin and PD values were compared between and within the groups.
Results The morning P-max value of group 1 was significantly higher than the value of group 2 (112 +/- 1 vs. 102 +/- 1 ms, P < 0.001). The morning PD of group 1 was significantly higher than that of group 2 (54 +/- 9 vs. 48 +/- 1 ms, P < 0.05). The morning P-max of group 1 (112 +/- 1 ms) was significantly higher than its afternoon 102 +/- 9 ms) and night (102 +/- 1 ms) values (P < 0.001). The morning PD of group 1 (54 +/- 9 ms) was higher than the afternoon (40 +/- 10 ms) and night (43 +/- 9 ms) PD (P < 0.001). No significant difference was observed between the P-max, P,in and PD values in group 2 (P > 0.05).
Conclusion This study demonstrated that coronary heart disease patients have higher morning P-max and PD values that may be important regarding prediction of timing and treatment of atrial conduction disorders in myocardial ischemia.