Influence of smoking on maternal and neonatal serum malondialdehyde, superoxide dismutase, and glutathione peroxidase levels
B Ermis, R Ors, A Yildirim, A Tastekin, F Kardas, F Akcay
article (Uluslararası, Hakemli) | Yazar(lar): B Ermis, R Ors, A Yildirim, A Tastekin, F Kardas, F Akcay | Yıl: 2004 | Dergi/Kurum: ANNALS OF CLINICAL AND LABORATORY SCIENCE | İndeks: WOS.SCI | Anahtar Kelimeler: smoking, pregnancy, newborns, malondialdehyde, glutathione peroxidase, superoxide dysmutase — Özet: This coh
This cohort study investigated postnatal serum malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPx) levels in 14 active-smoking, 14 passive-smoking, and 15 nonsmoking mothers and their newborns on day 7 post-partum. No significant differences were noted among the study groups with respect to MDA (p = 0.63) or SOD levels (p = 0.98) in either the mothers or their infants. However, there were significant differences among the study groups with respect to serum GPx activities in both the mothers (p = 0.028) and the infants (p = 0.039). When GPx activities were analyzed separately in both mothers and infants, a significant difference was noted only between the infants of smoking mothers and the infants of non-smoking mothers (p = 0.015). In conclusion, there was a significant increase in GPx activities of smoking mothers and their infants, suggesting that they may have been exposed to more oxidant stress.