Synthesis and characterization of polymeric linseed oil grafted methyl methacrylate or styrene
B Çakmakli, B Hazer, IO Tekin, S Kizgut, M Koksal, Y Menceloglu
article (Uluslararası, Hakemli) | Yazar(lar): B Çakmakli, B Hazer, IO Tekin, S Kizgut, M Koksal, Y Menceloglu | Yıl: 2004 | Dergi/Kurum: MACROMOLECULAR BIOSCIENCE | İndeks: WOS.SCI | DOI: 10.1002/mabi.200300117 | Anahtar Kelimeler: cell adhesion and proliferation, fibroplast cell, graft copolymers, linseed oil peroxide
Syntheses of wholly natural polymeric linseed oil (PLO) containing peroxide groups have been reported. Peroxidation, epoxidation and/or perepoxidation reactions of linseed oil, either under air or under oxygen flow at room temperature, resulted in polymeric peroxides, PLO-air and PLO-ofl, containing 1.3 and 3.5 wt.% of peroxide, with molecular weights of 2100 and 3780 Da, respectively. PLO-air contained cross-linked film up to 46.1 wt.% after a reaction time of 60 d, associated with a waxy, soluble part (PLO-air-s) that was isolated with chloroform extraction. PLO-ofl was obtained as a waxy, viscous liquid without any cross-linked part at the end of 24 d under visible irradation and oxygen flow. Polymeric peroxides, PLO-air-s and PLO-ofl initiated the free radical polymerization of both methyl methacrylate (MMA) and styreine (S) to give PMMA-graft-PLO and PS-graft-PLO graft copolymers in high yields with M(w) varying from 37 to 470 kDa. The polymers obtained were characterized by FT-IR. (1)H NMR, TGA, DSC and GPC techniques. Cross-linked polymers were also studied by means of swelling measurements. PMNA-graft-PLO graft copolymer film samples were also used in cell-culture studies. Fibroblast cells were well adhered and proliferated on the copolymer film surfaces, which is important in tissue engineering.