THE FOLLOW-UP RESULTS OF INSULIN PUMP USE IN TURKISH CHILDREN WITH TYPE I DIABETES MELLITUS
Mahmut Orhun Camurdan, Aysun Bideci, Peyami Cinaz, Fatma Demirel
article (Uluslararası, Hakemli) | Yazar(lar): Mahmut Orhun Camurdan, Aysun Bideci, Peyami Cinaz, Fatma Demirel | Yıl: 2008 | Dergi/Kurum: GAZI MEDICAL JOURNAL | İndeks: WOS.ESCI | Anahtar Kelimeler: Insulin Pump, Children, Type 1 Diabetes — Özet: Purpose: Although its use is increasing in children, there are no data ab
Purpose: Although its use is increasing in children, there are no data about pump use in Turkish children with diabetes. The aim of this study was to investigate the outcome measures of insulin pump use in diabetic Turkish children.
Materials and Methods: Ten children (age; 14.7 +/- 2.6 years, pump therapy duration; 3-24 months) were prospectively studied. Main outcome measures were compared with those of the 12 months prior to pump therapy.
Results: Although statistically insignificant, HbA1c tended to be lower compared to the pre-pump period. Body mass index Z scores remained similar (0.45 +/- 0.76 vs. 0.54 +/- 0.53 kg/m2, p>0.05). Insulin doses decreased (1.1 +/- 0.2 vs. 0.9 +/- 0.1 U/kg/day, p<0.01). Rates of certain episodes (event/patient-year) decreased: overall hyperglycemia; 244.0 +/- 84.5 vs. 90.6 +/- 38.9, Dawn phenomenon; 20.6 +/- 25.8 vs. 4.6 +/- 5.2, Somogyi phenomenon; 3.1 +/- 2.7 vs. 1.1 +/- 1.0, nocturnal hypoglycemia; 6.4 +/- 4.5 vs. 2.9 +/- 1.9, asymptomatic hypoglycemia; 21.3 +/- 13.4 vs. 8.8 +/- 6.7, symptomatic hypoglycemia; 3.7 +/- 2.2 vs. 1.6 +/- 1.3 (p values <0.05). Diabetic ketoacidosis rates were similar (0.24 vs. 0.30, p>0.05).
Conclusion: The consistency of the improvements in main outcome measures and their maintenance over time in our study suggest that pump therapy is safe and effective in diabetic Turkish children.